Description

(E)-2-(5-Methoxy)Phenol 4-(n-Benzyloxycarbonyl)Piperidinyl-Methanone Oxime is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, leveraging the piperidinyl and oxime functional groups for targeted activity.
• Chemical Biology Probes: Serves as a precursor for creating specialized molecular probes to study enzyme function and cellular signaling pathways.
• Peptidomimetic Synthesis: Integral to the construction of peptidomimetic compounds designed to mimic natural peptides with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	(E)-2-(5-Methoxy)Phenol 4-(n-Benzyloxycarbonyl)Piperidinyl-Methanone Oxime
CAS No.	84163-47-3
Molecular Formula	C21H24N2O5
Molecular Weight	384.43 g/mol
Synonyms	(E)-2-(5-Methoxyphenyl)-4-[(phenylmethoxy)carbonyl]-1-piperidinecarboxamide oxime; 4-(Benzyloxycarbonyl)-2-(5-methoxyphenyl)piperidine-1-carboxamide oxime; (Z)-N-[[4-[(Benzyloxy)carbonyl]-2-(5-methoxyphenyl)-1-piperidinyl]carbonyl]hydroxylamine; 84163-47-3; Oxime derivative of 4-(N-CBZ)-2-(5-methoxyphenyl)piperidine carboxamide
EINECS	Contact for details

Quality Control

Our (E)-2-(5-Methoxy)Phenol 4-(n-Benzyloxycarbonyl)Piperidinyl-Methanone Oxime is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.