Description

2-Chloro-1-Methylpyridinium Trifluoromethanesulphonate is a highly effective and versatile coupling reagent widely used in organic synthesis. This compound is valued for its ability to facilitate amide bond formation and esterification reactions under mild conditions, offering high yields with minimal racemization. It is an essential tool for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly in peptide synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Peptide Coupling Reagent: A key reagent for the formation of amide bonds in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Esterification Catalyst: Facilitates the condensation of carboxylic acids and alcohols to form esters.
• Agrochemical Synthesis: Employed in the production of herbicides, fungicides, and other crop protection agents.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, dyes, and fragrances.
• Bioconjugation: Applied in linking biomolecules for diagnostic and therapeutic applications.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and novel compound synthesis.

Basic Information

Item	Details
Product Name	2-Chloro-1-Methylpyridinium Trifluoromethanesulphonate
CAS No.	84030-18-2
Molecular Formula	C8H9ClF3NO3S
Molecular Weight	291.67 g/mol
Synonyms	1-Methyl-2-chloropyridinium trifluoromethanesulfonate; 2-Chloro-1-methylpyridinium triflate; Mukaiyama's Reagent; CMPT; 2-Chloro-1-methylpyridinium trifluoromethanesulfonate; 2-Chloro-1-methylpyridinium triflate; 1-Methyl-2-chloropyridinium trifluoromethanesulphonate; 2-Chloro-N-methylpyridinium trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Methylpyridinium Trifluoromethanesulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and KF titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.