Description

3-Cyclopropylcyclobutanone is a specialized organic compound featuring a cyclobutanone ring fused with a cyclopropyl substituent, creating a unique and sterically constrained molecular architecture. This structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for constructing complex, three-dimensional frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring strained ring systems to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the cyclopropyl and cyclobutanone motifs can contribute to unique modes of action.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in cycloaddition reactions, ring-expansion transformations, and as a scaffold for constructing complex natural product analogs and chemical libraries for high-throughput screening.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands or organocatalysts that leverage its rigid, three-dimensional structure for asymmetric synthesis.
• Flavor and Fragrance Chemistry: Investigated as an intermediate for synthesizing novel aroma compounds with unique olfactory characteristics.

Basic Information

Product Name	3-Cyclopropylcyclobutanone
CAS No.	83961-08-4
Molecular Formula	C7H10O
Molecular Weight	110.15 g/mol
Synonyms	Cyclopropyl cyclobutanone; Cyclobutanone, 3-cyclopropyl-; 3-Cyclopropylcyclobutan-1-one; 1-Cyclopropylcyclobutan-3-one; NSC 406915; 83961-08-4; Cyclopropylcyclobutanone
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylcyclobutanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for research-grade chemicals to guarantee reliable and reproducible performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.