Description

4'-Isocyanato-5'-Nitrobenzo-15-Crown-5, 99.5% is a high-purity, functionalized crown ether derivative designed for advanced chemical synthesis and materials science applications. This compound is valued for its dual functionality, combining the selective cation-binding properties of a 15-crown-5 ether with a reactive isocyanate group and an electron-withdrawing nitro substituent. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel supramolecular assemblies, selective sensors, and functional materials.

Application

• Supramolecular Chemistry & Host-Guest Systems: Acts as a key building block for synthesizing sophisticated molecular receptors and sensors due to its crown ether cavity and reactive handle.
• Polymer Modification & Functional Materials: The reactive isocyanate group enables covalent attachment to polymers, surfaces, or other matrices to create ion-selective membranes, coatings, or smart materials.
• Pharmaceutical Intermediate: Used in the research and development of complex drug molecules where precise molecular recognition or controlled release properties are required.
• Catalysis & Ligand Design: Serves as a precursor for creating specialized ligands that can modulate the activity and selectivity of metal catalysts in organic synthesis.
• Analytical Chemistry & Separation Science: Employed in the development of stationary phases for chromatography or extraction media for selective ion binding and separation.
• Academic & Industrial R&D: A critical reagent for fundamental research in organic synthesis, coordination chemistry, and the development of new functional nanomaterials.

Basic Information

Product Name	4'-Isocyanato-5'-Nitrobenzo-15-Crown-5, 99.5%
CAS No.	83935-64-2
Molecular Formula	C17H22N2O8
Molecular Weight	382.37 g/mol
Synonyms	5'-Nitrobenzo-15-crown-5-4'-yl isocyanate; 1-Isocyanato-4,7,10,13-tetraoxa-16-aza-2-nitrocyclooctadeca-1,3,16-triene; 4-Isocyanato-5-nitrobenzo-15-crown-5; Nitrobenzo-15-crown-5 isocyanate; Functionalized 15-Crown-5 Ether; Isocyanato Nitrobenzo Crown Ether; 15-Crown-5-Nitro-Isocyanate Derivative; B15C5-NO2-NCO
EINECS	Contact for details

Quality Control

Our 4'-Isocyanato-5'-Nitrobenzo-15-Crown-5 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and FT-IR to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.5%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Single Impurity (HPLC)	≤ 0.2%
Total Impurities (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.