Description

2,5,8,11-Tetraazadodecanediamidine Dihydrochloride is a high-purity, polyamine-based chemical building block with a defined cationic structure. This compound is valued for its ability to interact with and modify anionic substrates, making it a critical intermediate in advanced research and specialty synthesis. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for developing novel therapeutic agents, gene delivery systems, and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel polycationic drugs, including potential antimicrobial and antiviral agents.
• Bioconjugation & Probe Development: Used to create fluorescent or affinity tags for labeling biomolecules like proteins and nucleic acids in diagnostic assays.
• Gene Delivery Research: Investigated as a component in the design of non-viral vectors (polyplexes) for cellular transfection and gene therapy applications.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for producing specialty polyamides, polyamines, and ion-exchange resins.
• Surface Modification: Employed to coat materials to impart a positive charge, enhancing adhesion or creating antimicrobial surfaces.
• Catalysis: May function as a ligand or co-catalyst in organic synthesis and polymerization reactions.
• Analytical Chemistry: Used as a standard or reagent in method development for analyzing polyamine compounds.

Basic Information

Product Name	2,5,8,11-Tetraazadodecanediamidine Dihydrochloride
CAS No.	83898-08-2
Molecular Formula	C10H28N8·2HCl
Molecular Weight	345.32 g/mol (Free base: 272.39 g/mol)
Synonyms	1,12-Diamidino-4,9-diazadodecane Dihydrochloride; N,N'-Bis(3-amidinopropyl)-1,3-propanediamine Dihydrochloride; 1,12-Bis(amidino)-4,9-diazadodecane Dihydrochloride; NSC 339638 Dihydrochloride; Tetraazadodecanediamidine Dihydrochloride; Spermine Amidine Analog Dihydrochloride; Polyamine Amidine Dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2,5,8,11-Tetraazadodecanediamidine Dihydrochloride is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting research reproducibility and process development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Chloride Content (Titration)	Theoretical ± 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.