Description

(R)-Chroman-2-Carboxylic Acid CAS NO 83780-47-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its well-defined stereochemistry, which is critical for imparting specific biological activity in final target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for cardiovascular and central nervous system (CNS) disorders.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective chemical reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed reactions and organocatalysts.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic and R&D: Utilized in university and institutional research for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(R)-Chroman-2-Carboxylic Acid
CAS No.	83780-47-6
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(R)-2-Chromancarboxylic Acid; (2R)-3,4-Dihydro-2H-1-benzopyran-2-carboxylic Acid; (R)-2,3-Dihydro-1-benzopyran-2-carboxylic Acid; (R)-Dihydrocoumarin-2-carboxylic Acid; (R)-Chroman-2-carboxylic acid; (R)-2-Carboxychroman; (R)-2,3-Dihydro-2H-chromene-2-carboxylic acid; (R)-2,3-Dihydro-2H-1-benzopyran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (R)-Chroman-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.