Description

(R)-o-Isopropylidene Glycerol Mesylate is a high-value chiral building block and pharmaceutical intermediate. This compound matters for its role in the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for producing enantiomerically pure products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of antiviral, anticancer, and cardiovascular drugs.
• Nucleoside & Nucleotide Chemistry: Used in the preparation of modified nucleosides and nucleotides for medicinal chemistry and biochemical research.
• Asymmetric Synthesis: Serves as a versatile starting material for constructing complex, enantiomerically pure natural products and bioactive compounds.
• Agrochemical Synthesis: Intermediate in the production of chiral pesticides and herbicides.
• Polymer Chemistry: Monomer for creating specialized polymers with controlled stereochemistry.
• Ligand & Catalyst Preparation: Building block for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.

Basic Information

Product Name	(R)-o-Isopropylidene Glycerol Mesylate
CAS No.	83461-40-9
Molecular Formula	C7H14O5S
Molecular Weight	210.25 g/mol
Synonyms	(R)-(-)-1,2-O-Isopropylidene-3-O-methanesulfonylglycerol; (R)-(-)-1,2-O-Isopropylidene-3-O-mesylglycerol; (R)-1,2-O-Isopropylidene-3-O-methanesulfonyl-sn-glycerol; (R)-(-)-1,2-Isopropylidene Glyceryl Methanesulfonate; (R)-(-)-1,2-O-Isopropylidene Glyceryl Mesylate; (R)-(-)-1,2-O-Isopropylidene-3-O-(methylsulfonyl)glycerol; (R)-(-)-1,2-O-Isopropylidene-3-O-(methanesulfonyl)-sn-glycerol; (R)-(-)-1,2-O-Isopropylidene-3-O-mesyl-sn-glycerol
EINECS	Contact for details

Quality Control

Our (R)-o-Isopropylidene Glycerol Mesylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with high-purity standards for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.