Description

Potassium 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate is a versatile potassium salt derivative of a protected glyceric acid, serving as a key chiral building block and intermediate in sophisticated organic synthesis. Its primary value lies in providing a reactive carboxylate functionality while the acetonide group protects sensitive diol moieties, enabling selective transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, enantiomerically pure intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of β-blockers, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the glyceric acid skeleton is a key structural component.
• Specialty Polymer Monomer: Acts as a functional monomer for introducing hydrophilic and biodegradable segments into polymers for controlled-release or specialty coating applications.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enhancing reaction selectivity and yield.
• Bioconjugation and Prodrug Development: Utilized in medicinal chemistry to create biodegradable linkers or to modify drug molecules for improved solubility and targeted delivery.
• Fine Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Item	Details
Product Name	Potassium 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate
CAS No.	83400-91-3
Molecular Formula	C7H11KO4
Molecular Weight	198.26 g/mol
Synonyms	Potassium (2,2-Dimethyl-1,3-dioxolan-4-yl)formate; Potassium (4R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylate; Potassium D-Glycerate Acetonide; Potassium (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxylate; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt; Glyceric Acid, 2,3-O-Isopropylidene-, Potassium Salt; Acetonide-Protected Glyceric Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). To maintain purity and prevent decomposition, the container must be kept tightly sealed in a dry environment and allowed to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (R)
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.