Description

2-Pentanone, 1-Chloro-5-Fluoro-3,3-Dimethyl- is a specialized halogenated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a dimethylated pentanone backbone, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce specific halogenated motifs that can influence bioactivity, metabolic stability, and physical characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated and chlorinated groups to modulate drug potency and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated structure contributes to biological activity and environmental persistence profiles.
• Material Science Research: Acts as a precursor for synthesizing specialty polymers, liquid crystals, or organic electronic materials that require specific halogenated components.
• Organic Synthesis Building Block: Employed in academic and industrial R&D labs for constructing complex organic molecules, leveraging its reactive ketone and halogen functional groups for further chemical transformations.
• Fluorochemical Production: A potential intermediate in the synthesis of more complex fluorinated compounds used in various high-performance industrial applications.

Basic Information

Product Name	2-Pentanone, 1-Chloro-5-Fluoro-3,3-Dimethyl-
CAS No.	83391-83-7
Molecular Formula	C7H12ClFO
Molecular Weight	166.62 g/mol
Synonyms	1-Chloro-5-fluoro-3,3-dimethylpentan-2-one; 3,3-Dimethyl-1-chloro-5-fluoropentan-2-one; 1-Chloro-5-fluoro-3,3-dimethyl-2-pentanone; 83391-83-7; Pentan-2-one, 1-chloro-5-fluoro-3,3-dimethyl-
EINECS	Contact for details

Quality Control

We supply 2-Pentanone, 1-Chloro-5-Fluoro-3,3-Dimethyl- in high-purity grades suitable for research and industrial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.