Description

Carbodiimide Homopolymer is a versatile polymeric compound widely recognized for its exceptional properties as a zero-length crosslinker and dehydrating agent. Its primary commercial value lies in its ability to efficiently mediate the formation of amide bonds between carboxylic acids and amines, making it a critical reagent in peptide synthesis and bioconjugation. This product is essential for R&D laboratories, pharmaceutical manufacturers, and biotechnology companies engaged in the development of novel therapeutic agents, diagnostic tools, and advanced biomaterials.

Application

• Peptide Synthesis: As a key coupling agent for the formation of peptide bonds in solid-phase and solution-phase synthesis.
• Bioconjugation: For the stable crosslinking of proteins, antibodies, enzymes, and other biomolecules to carriers, surfaces, or other molecules.
• Polymer Chemistry: Used as a chain extender or crosslinker in the production of polyurethanes, polyureas, and other specialty polymers to enhance material properties.
• Carboxylic Acid Activation: Facilitates the conversion of carboxylic acids into active esters or anhydrides for subsequent reactions in organic synthesis.
• Hydrolysis Inhibition: Acts as a scavenger for water and carboxylic acids in sensitive chemical reactions to prevent side reactions and improve yields.
• Surface Modification: Employed to functionalize material surfaces (e.g., nanoparticles, chips) with amine-containing ligands for biosensing and diagnostic applications.

Basic Information

Item	Detail
Product Name	Carbodiimide Homopolymer
CAS No.	83138-86-7
Molecular Formula	(C2H4N2)n
Molecular Weight	Variable (Polymer)
Synonyms	Polycarbodiimide; Poly(1,3-Di-p-tolylcarbodiimide); Poly(1,3-Di-o-tolylcarbodiimide); Carbodiimide Resin; EDC Polymer; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Homopolymer; Water-Soluble Carbodiimide; Crosslinking Agent CDI
EINECS	Contact for details

Quality Control

Our Carbodiimide Homopolymer is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including assay by titration, infrared spectroscopy (IR) for identification, and residual solvent analysis to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (Carbodiimide Content)	≥ 95.0 %
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.