Description

Methanesulfonic Acid, Trifluoro-, 1,1-Dimethylethyl Ester is a specialized fluorinated sulfonate ester, a key reagent in advanced organic synthesis. This compound matters for its role as a versatile protecting group and alkylating agent, particularly valuable in the synthesis of complex molecules where its tert-butyl ester group offers specific reactivity and stability advantages. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate Synthesis: Employed as a key building block and protecting group in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated compounds.
• Agrochemical Manufacturing: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethanesulfonyl moiety enhances biological activity and stability.
• Polymer & Material Science: Acts as a monomer or modifying agent in the development of specialty polymers, including fluoropolymers with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Serves as a potent alkylating agent and a source of the trifluoromethanesulfonate (triflate) anion in cross-coupling reactions and catalysis.
• Ligand & Catalyst Preparation: Utilized in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Laboratory Research: A critical reagent for method development and exploratory chemistry in academic and industrial R&D settings focused on fluorine chemistry.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 1,1-Dimethylethyl Ester
CAS No.	82951-44-8
Molecular Formula	C6H11F3O3S
Molecular Weight	220.21 g/mol
Synonyms	tert-Butyl Trifluoromethanesulfonate; tert-Butyl Triflate; Trifluoromethanesulfonic Acid tert-Butyl Ester; 1,1-Dimethylethyl Trifluoromethanesulfonate; t-Butyl Triflate; t-BuOTf; tert-Butyl Perfluoroalkanesulfonate
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, Trifluoro-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.