Description

4-Hydroxy-3-Hydroxymethyl-Benzoic Acid is a multifunctional aromatic compound featuring both phenolic and carboxylic acid groups, making it a valuable intermediate in advanced organic synthesis. Its unique structure allows for selective functionalization, enabling the creation of complex molecules with tailored properties. This chemical is essential for research and development in the pharmaceutical and fine chemical industries, where it serves as a key building block for active pharmaceutical ingredients (APIs), specialty polymers, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for compounds requiring a functionalized benzoic acid core.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules, including ligands, catalysts, and specialty monomers in research and development.
• Polymer Chemistry: Used in the production of specialty polymers and resins, where its dual functionality can be incorporated into polymer backbones to modify thermal or mechanical properties.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of new herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the development of advanced organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Bioconjugation & Linker Chemistry: Its carboxylic acid and hydroxyl groups make it suitable for creating cleavable linkers and modifying biomolecules in bioconjugation applications.

Basic Information

Product Name	4-Hydroxy-3-Hydroxymethyl-Benzoic Acid
CAS No.	82885-62-9
Molecular Formula	C9H10O5
Molecular Weight	198.17 g/mol
Synonyms	3-(Hydroxymethyl)-4-hydroxybenzoic acid; 4-Hydroxy-3-(hydroxymethyl)benzoic acid; Benzoic acid, 4-hydroxy-3-(hydroxymethyl)-; 3-Carboxymethylsalicylic acid (ambiguous); 4-Hydroxyisophthalic alcohol; 3-Hydroxymethyl-4-hydroxybenzoic acid; 5-Carboxy-2-hydroxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Hydroxymethyl-Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates, including cGMP-grade material for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.