Description

3-Penten-2-One, 5,5-Difluoro-4-Hydroxy- (9Ci) is a specialized fluorinated ketone building block with a unique α-hydroxy-α,α-difluoro carbonyl motif. This compound is valued for its ability to introduce fluorine atoms and a reactive ketone handle into complex molecular architectures, significantly altering physical and biological properties. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro group can enhance lipophilicity and metabolic stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and coatings with tailored surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via reactions at the ketone and hydroxyl functional groups.
• Fluorine Chemistry Research: An essential reagent for studying the effects of gem-difluoro substitution adjacent to carbonyl groups in chemical reactions and material science.

Basic Information

Product Name	3-Penten-2-One, 5,5-Difluoro-4-Hydroxy- (9Ci)
CAS No.	82750-11-6
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	5,5-Difluoro-4-hydroxypent-3-en-2-one; 4-Hydroxy-5,5-difluoro-3-penten-2-one; 5,5-Difluoro-4-hydroxy-3-penten-2-one; α,α-Difluoro-β-hydroxyvinyl methyl ketone; 1,1-Difluoro-2-(1-hydroxyethylidene)ethan-1-ol (tautomeric form); Difluorohydroxypentenone; 82750-11-6
EINECS	Contact for details

Quality Control

Every batch of 3-Penten-2-One, 5,5-Difluoro-4-Hydroxy- (9Ci) is manufactured and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its functional groups, prolonged exposure to moisture or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.