Description

Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)-, (Z)- (9Ci) is a high-purity fluorinated cyclopentanone derivative, identified by CAS NO 82726-78-1. This compound serves as a versatile and critical building block in advanced organic synthesis, prized for its unique trifluoromethyl and hydroxyl-substituted alkene functionality. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination.

Basic Information

Product Name	Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)-, (Z)- (9Ci)
CAS No.	82726-78-1
Molecular Formula	C7H7F3O2
Molecular Weight	180.13 g/mol
Synonyms	(Z)-2-(2,2,2-Trifluoro-1-hydroxyethylidene)cyclopentanone; 2-[(1Z)-2,2,2-Trifluoro-1-hydroxyethylidene]cyclopentanone; 2-(2,2,2-Trifluoro-1-hydroxyethylidene)cyclopentanone; (Z)-2-(Trifluoroacetyl)cyclopentanone enol; 82726-78-1; 2-(2,2,2-Trifluoro-1-hydroxyethylidene)cyclopentan-1-one; (1Z)-2,2,2-Trifluoro-1-(2-oxocyclopentylidene)ethanol
EINECS	Contact for details

Quality Control

Our Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)-, (Z)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP and ISO 9001 principles for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.