Description

4-(Trimethylsilyl)-1H-Indole 98 CAS NO 82645-11-2 is a high-purity organosilicon derivative of indole, serving as a versatile and valuable protected intermediate in advanced organic synthesis. Its primary value lies in its role as a key building block for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This product is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial protected synthon for the synthesis of novel indole-based drug candidates, including kinase inhibitors and serotonin receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the indole scaffold provides key biological activity.
• Material Science Research: Acts as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Academic & R&D Laboratories: Employed in methodological development and the synthesis of complex natural product analogs and chemical libraries.
• Fine Chemical Production: Serves as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	4-(Trimethylsilyl)-1H-Indole 98
CAS No.	82645-11-2
Molecular Formula	C11H15NSi
Molecular Weight	189.33 g/mol
Synonyms	4-(Trimethylsilyl)-1H-indole; 1H-Indole, 4-(trimethylsilyl)-; 4-Trimethylsilylindole; 4-TMS-indole; 4-(TMS)indole; 4-(Trimethylsilyl)indole; 4-Indolyltrimethylsilane
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure a typical purity of ≥98% and conformity to specification. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.