Description

(3B,5B,15A,16A)-15,16-Dihydro-3,5-Dihydroxy-3'H-Cycloprop[15,16]Androsta-6,15-Dien-17-One is a high-purity, advanced steroidal intermediate of significant interest in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to develop new drug candidates with modified steroidal frameworks. The compound, CAS 82543-15-5, is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental outcomes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Research & Development: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of modified steroidal compounds.
• Process Chemistry: Serves as a starting material or intermediate in the development and scale-up of complex synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating enzyme inhibition or modulation of specific metabolic pathways involving steroidal structures.

Basic Information

Product Name	(3B,5B,15A,16A)-15,16-Dihydro-3,5-Dihydroxy-3'H-Cycloprop[15,16]Androsta-6,15-Dien-17-One
CAS No.	82543-15-5
Molecular Formula	C20H26O3
Molecular Weight	314.42 g/mol
Synonyms	15,16-Dihydro-3,5-dihydroxy-3'H-cyclopropa[15,16]androsta-6,15-dien-17-one; (3β,5β,15α,16α)-15,16-Dihydro-3,5-dihydroxy-3'H-cyclopropa[15,16]androsta-6,15-dien-17-one; Steroidal cyclopropane derivative; 3'H-Cycloprop[15,16]androsta-6,15-dien-17-one, 15,16-dihydro-3,5-dihydroxy-, (3β,5β,15α,16α)-; CAS 82543-15-5
EINECS	Contact for details

Quality Control

Our (3B,5B,15A,16A)-15,16-Dihydro-3,5-Dihydroxy-3'H-Cycloprop[15,16]Androsta-6,15-Dien-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.