Description

4-Bromo-2-Nitrobenzyl Bromide is a versatile and highly reactive halogenated aromatic compound, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its bromine and nitro groups, which facilitate selective functionalization for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring benzyl-protected or halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitro and bromo substituents impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or photoactive compounds.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations due to the reactive bromine atom.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes for studying biological systems.

Basic Information

Product Name	4-Bromo-2-Nitrobenzyl Bromide
CAS No.	82420-34-6
Molecular Formula	C7H5Br2NO2
Molecular Weight	294.93 g/mol
Synonyms	1-(Bromomethyl)-4-bromo-2-nitrobenzene; 2-Nitro-4-bromobenzyl Bromide; 4-Bromo-2-nitrobenzyl Bromide; 4-Bromo-2-nitro-α-bromotoluene; (4-Bromo-2-nitrophenyl)methyl Bromide; α,4-Dibromo-2-nitrobenzyl Bromide; Benzene, 1-(bromomethyl)-4-bromo-2-nitro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Nitrobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.