Description

[1-(7-Bromobicyclo[4.1.0]Hept-7-Yl)Propoxy]Trimethylsilane is a specialized organosilicon compound featuring a reactive brominated bicyclic moiety. This unique structure makes it a valuable advanced synthetic intermediate for constructing complex molecular architectures in pharmaceutical and material science research. It is primarily needed by R&D chemists and process development scientists working in organic synthesis, medicinal chemistry, and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring strained ring systems.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce unique steric and electronic properties.
• Functional Material Precursor: Acts as a monomer or cross-linking agent in the development of specialty silicones and advanced polymers with tailored properties.
• Agrochemical Synthesis: Employed in the research and development of new crop protection agents and herbicides.
• Ligand and Catalyst Development: Utilized to create novel chiral ligands or organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Facilitates the synthesis of molecular probes for studying biological systems and target engagement.

Basic Information

Item	Details
Product Name	[1-(7-Bromobicyclo[4.1.0]Hept-7-Yl)Propoxy]Trimethylsilane
CAS No.	82253-03-0
Molecular Formula	C13H25BrOSi
Molecular Weight	305.33 g/mol
Synonyms	Trimethyl[1-(7-bromobicyclo[4.1.0]hept-7-yl)propoxy]silane; 1-(7-Bromobicyclo[4.1.0]hept-7-yl)propoxytrimethylsilane; 7-Bromo-7-(3-trimethylsilyloxypropyl)bicyclo[4.1.0]heptane; (7-Bromo-7-bicyclo[4.1.0]heptylpropoxy)trimethylsilane; 82253-03-0; Bicyclo[4.1.0]heptane, 7-bromo-7-[3-[(trimethylsilyl)oxy]propyl]-
EINECS	Contact for details

Quality Control

Our [1-(7-Bromobicyclo[4.1.0]Hept-7-Yl)Propoxy]Trimethylsilane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing including NMR, HPLC, and GC to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.