Description

1-tert-Butyl-n-(1-((tert-Butyldimethylsilyl)Oxy)Butan-2-Yl)-1,1-Dimethylsilanamine is a specialized organosilicon compound featuring a unique silylamine and silyl ether-protected alcohol functional group. This dual functionality makes it a valuable protected intermediate and ligand precursor in advanced synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular architectures.

Application

• Advanced Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly where sterically hindered amine or silicon-containing motifs are required.
• Organometallic Catalyst Ligand: Acts as a precursor for nitrogen-silicon chelating ligands used in transition metal catalysis for asymmetric synthesis and cross-coupling reactions.
• Silicon-Based Polymer Chemistry: Employed in the research and development of specialty silicones and silane-modified polymers, contributing to unique material properties.
• Protecting Group Strategy: The tert-butyldimethylsilyl (TBDMS) ether group provides a stable protecting group for alcohols during multi-step synthetic sequences, which can be selectively removed under mild conditions.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides that incorporate silicon to enhance stability and bioavailability.
• Material Science Research: Investigated for surface modification, adhesion promotion, and as a coupling agent in composite materials.

Basic Information

Item	Detail
Product Name	1-tert-Butyl-n-(1-((tert-Butyldimethylsilyl)Oxy)Butan-2-Yl)-1,1-Dimethylsilanamine
CAS No.	82112-34-3
Molecular Formula	C16H37NO2Si2
Molecular Weight	331.65 g/mol
Synonyms	N-(1-((tert-Butyldimethylsilyl)oxy)butan-2-yl)-1,1-dimethyl-N-(tert-butyl)silanamine; 1,1-Dimethyl-N-(tert-butyl)-N-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-butyl]silanamine; tert-Butyl(1-((tert-butyldimethylsilyl)oxy)butan-2-yl)(dimethyl)silylamine; Silanamine, N-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-butyl]-1,1-dimethyl-N-(1,1-dimethylethyl)-; TBDMS-protected silylamine; tert-Butyl(dimethyl)[1-[(tert-butyldimethylsilyl)oxy]butan-2-yl]silylamine
EINECS	Contact for details

Quality Control

Our production of 1-tert-Butyl-n-(1-((tert-Butyldimethylsilyl)Oxy)Butan-2-Yl)-1,1-Dimethylsilanamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analysis including NMR (¹H, ¹³C, ²⁹Si), HPLC/GC purity assay, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
¹H NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.