Description

(R)-2-Methyltetrahydropyran-4-One CAS NO 82110-22-3 is a chiral, non-racemic heterocyclic ketone of significant synthetic utility. This high-purity enantiomer is a critical building block for the asymmetric synthesis of complex pharmaceutical intermediates and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and antiviral agents.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Flavor and Fragrance Chemistry: Employed in the synthesis of chiral odorants and flavoring agents where stereochemistry influences the sensory profile.
• Material Science Research: Investigated as a monomer or precursor for chiral polymers and advanced organic materials with specific optical properties.
• Academic and Process R&D: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	(R)-2-Methyltetrahydropyran-4-One
CAS No.	82110-22-3
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(R)-2-Methyl-4-oxotetrahydropyran; (R)-2-Methyl-4-tetrahydropyranone; (R)-2-Methyl-4-oxooxane; (R)-2-Methyl-4-oxotetrahydro-2H-pyran; (R)-2-Methyl-4-oxotetrahydropyran-4-one; (R)-2-Methyltetrahydro-4H-pyran-4-one; (R)-2-Methyl-4-oxotetrahydropyranone; (R)-2-Methyl-4-oxotetrahydropyran-4-ol (tautomer)
EINECS	Contact for details

Quality Control

Our (R)-2-Methyltetrahydropyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by chiral HPLC or GC, identity confirmation by IR and NMR spectroscopy, and quantification of organic impurities. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Water Content (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.