Description

(2R,4S)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol CAS NO 82110-16-5 is a chiral, non-racemic organic compound featuring a phenyl-substituted tetrahydropyran ring with a secondary alcohol functional group. This specific stereochemistry makes it a valuable chiral building block and intermediate in asymmetric synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for the production of active pharmaceutical ingredients (APIs), agrochemicals, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-infective agents.
• Asymmetric Catalysis Ligand Precursor: Used in the development and synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides, where stereochemistry can impact efficacy and environmental profile.
• Fine Chemical and Flavor & Fragrance Intermediate: Employed in the multi-step synthesis of complex aroma chemicals and other high-purity specialty organic compounds.
• Academic and Industrial R&D: Utilized in methodological research for developing new synthetic routes and studying stereochemical outcomes in organic reactions.

Basic Information

Product Name	(2R,4S)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol
CAS No.	82110-16-5
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(2R,4S)-2-Phenyl-4-hydroxytetrahydropyran; (2R,4S)-2-Phenyltetrahydro-4-pyranol; (2R,4S)-4-Hydroxy-2-phenyltetrahydropyran; 2-Phenyltetrahydropyran-4-ol (specifying (2R,4S) isomer); cis-2-Phenyl-4-hydroxytetrahydropyran (relative stereochemistry); Chiral Pyranol Intermediate; 82110-16-5
EINECS	Contact for details

Quality Control

Our (2R,4S)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation or moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.