Description

2-Methyl-4-[(1S)-1,2,2-Trimethylcyclopentyl]Phenol is a chiral phenolic compound featuring a complex, hindered cyclopentyl structure. This molecular architecture is critical for its role as a high-value intermediate and building block in advanced organic synthesis. It is primarily sought by R&D and production teams in the fragrance, pharmaceutical, and specialty chemical industries for creating novel compounds with specific stereochemical and functional properties.

Application

• Fragrance & Flavor Intermediate: Serves as a key precursor for synthesizing novel amber, woody, and musk aroma chemicals, leveraging its chiral and sterically hindered phenol group.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs) where its specific stereochemistry and phenolic functionality are essential.
• Specialty Polymer Additive: Acts as a monomer or functional modifier in the synthesis of high-performance polymers, contributing antioxidant or other specific properties.
• Agrochemical Synthesis: Employed as an intermediate in creating advanced crop protection agents with tailored activity.
• Liquid Crystal & Electronic Materials: Utilized in the development of organic electronic materials and liquid crystal displays due to its rigid, asymmetric structure.
• Catalyst Ligand Precursor: The phenolic and chiral nature makes it a candidate for developing novel ligands in asymmetric catalysis.

Basic Information

Product Name	2-Methyl-4-[(1S)-1,2,2-Trimethylcyclopentyl]Phenol
CAS No.	81784-09-0
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	4-[(1S)-1,2,2-Trimethylcyclopentyl]-2-methylphenol; (S)-2-Methyl-4-(1,2,2-trimethylcyclopentyl)phenol; Phenol, 2-methyl-4-[(1S)-1,2,2-trimethylcyclopentyl]-; Ambroxide precursor; 1-(2-Hydroxy-5-methylphenyl)-2,2,3-trimethylcyclopentane (S-enantiomer); Musk phenol intermediate; Chiral hindered phenol
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-[(1S)-1,2,2-Trimethylcyclopentyl]Phenol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon blanket). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.