Description

(2S,3S)-3-Hydroxy-2-Methylcyclopentanone is a chiral, non-racemic cyclopentanone derivative of significant interest in fine chemical synthesis. This compound matters as a versatile chiral building block and intermediate for the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that need this high-value intermediate include pharmaceutical R&D for active pharmaceutical ingredient (API) synthesis, fragrance and flavor manufacturing, and advanced material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where the stereoisomer can affect biological activity and environmental persistence.
• Fragrance & Flavor Ingredient: Serves as a precursor for musky or woody odorants and complex flavor compounds due to its cyclopentanone backbone.
• Asymmetric Catalysis Research: Employed as a test substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Organic Synthesis Building Block: Utilized in stereoselective reactions, such as aldol condensations or reductions, to construct more complex, optically active structures.
• Material Science: Potential monomer or modifier for synthesizing specialized polymers with tailored optical or physical properties.

Basic Information

Product Name	(2S,3S)-3-Hydroxy-2-Methylcyclopentanone
CAS No.	81779-56-8
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(2S,3S)-2-Methyl-3-hydroxycyclopentanone; (2S,3S)-3-Hydroxy-2-methylcyclopentan-1-one; (-)-(2S,3S)-3-Hydroxy-2-methylcyclopentanone; L-erythro-3-Hydroxy-2-methylcyclopentanone; (2S,3S)-HMCP; 2-Methyl-3-hydroxycyclopentanone (stereospecific)
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-Hydroxy-2-Methylcyclopentanone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.