Description

2-(2-Fluorophenyl)-1,2-Benzisoselenazol-3(2H)-One is a specialized organoselenium compound of significant interest in advanced chemical synthesis and pharmaceutical research. Its unique benzisoselenazolone scaffold, functionalized with a fluorophenyl group, makes it a valuable building block for developing novel therapeutic agents and functional materials. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for its role in creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those exploring selenium-based pharmacophores for antioxidant, anti-inflammatory, or anticancer activity.
• Agrochemical Research: Used in developing new generation pesticides and fungicides, where the selenium moiety can contribute to unique modes of action.
• Chemical Biology Probe: Employed in research to study selenoprotein mimics and enzyme inhibition, aiding in understanding redox biology and disease mechanisms.
• Material Science: Investigated as a monomer or additive for creating specialized polymers and organic electronic materials with enhanced properties.
• Catalyst Development: Acts as a ligand or precursor for designing novel organoselenium catalysts used in green chemistry and asymmetric synthesis.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists exploring new heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	2-(2-Fluorophenyl)-1,2-Benzisoselenazol-3(2H)-One
CAS No.	81743-95-5
Molecular Formula	C₁₃H₈FNOSe
Molecular Weight	300.17 g/mol
Synonyms	2-(2-Fluorophenyl)-1,2-benzisoselenazol-3(2H)-one; 2-(2-Fluorophenyl)-1,2-benzoselenazol-3-one; 2-(o-Fluorophenyl)-1,2-benzisoselenazol-3(2H)-one; Ebselen analog; PZ51 analog; Selenazole derivative; Fluorinated ebselen derivative; 1,2-Benzisoselenazol-3(2H)-one, 2-(2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)-1,2-Benzisoselenazol-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in DMSO, DMF; slightly soluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.