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4-Chloro-3-Methylbenzeneacetic Acid CAS NO 81720-78-7


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CAS No.:81720-78-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-3-Methylbenzeneacetic Acid is a versatile chlorinated aromatic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid group and a chloro-methyl substitution pattern, makes it a valuable intermediate for creating compounds with specific steric and electronic properties. This chemical is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

  • Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting inflammatory or central nervous system pathways.
  • Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where the chlorinated aromatic core contributes to biological activity.
  • Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays, leveraging its aromatic structure for molecular stability.
  • Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal or chemical resistance.
  • Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and pigments, where it helps introduce specific color properties and fastness.
  • Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name 4-Chloro-3-Methylbenzeneacetic Acid
CAS No. 81720-78-7
Molecular Formula C9H9ClO2
Molecular Weight 184.62 g/mol
Synonyms 2-(4-Chloro-3-methylphenyl)acetic Acid; (4-Chloro-3-methylphenyl)acetic Acid; 4-Chloro-m-tolylacetic Acid; 4-Chloro-3-methylbenzene acetic acid; 4-Chloro-3-methylbenzenacetic acid; 4-Chloro-3-methylphenylacetic acid; p-Chloro-m-tolylacetic Acid; NSC 406925
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Quality Control

Our 4-Chloro-3-Methylbenzeneacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material is suitable for demanding applications in regulated industries, supporting your R&D and production needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its acidic nature, store separately from strong bases, oxidizing agents, and reactive metals. Keep the container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 105 - 110 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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