Description

3-Butyn-2-One, 1,1-Dichloro-4-Methoxy- is a specialized halogenated alkynone building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both an alkyne and a dichloromethyl ketone moiety, makes it a versatile precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for novel polymers, liquid crystals, and organic electronic materials due to its reactive functional groups.
• Chemical Biology Probes: Employed in the creation of activity-based probes and molecular tags for studying biological pathways.
• Cross-Coupling Reactions: Acts as a substrate in Sonogashira and other palladium-catalyzed cross-coupling reactions to create complex conjugated systems.
• Heterocyclic Chemistry: A crucial starting material for the synthesis of various nitrogen- and oxygen-containing heterocycles, such as pyrazoles and isoxazoles.

Basic Information

Product Name	3-Butyn-2-One, 1,1-Dichloro-4-Methoxy-
CAS No.	81711-47-9
Molecular Formula	C6H6Cl2O2
Molecular Weight	181.02 g/mol
Synonyms	1,1-Dichloro-4-methoxy-3-butyn-2-one; 4-Methoxy-1,1-dichloro-3-butyn-2-one; 1,1-Dichloro-4-methoxybut-3-yn-2-one; Dichloro(methoxy)butynone; Methoxydichlorobutynone
EINECS	Contact for details

Quality Control

Our 3-Butyn-2-One, 1,1-Dichloro-4-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its reactive functional groups, it should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.