Description

1H-Imidazole, 2-(2,6-Dichlorophenyl)-5-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl-substituted imidazole core. This compound is critical for advanced organic synthesis, offering a versatile scaffold for creating molecules with tailored electronic and steric properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazole and trifluoromethyl groups.
• Material Science Research: Serves as a building block for advanced organic materials, including ligands for catalysis and components for organic electronic devices.
• Chemical Biology & Proteomics: Employed as a specialized scaffold or tag in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex APIs.

Basic Information

Product Name	1H-Imidazole, 2-(2,6-Dichlorophenyl)-5-(Trifluoromethyl)-
CAS No.	81654-11-7
Molecular Formula	C10H5Cl2F3N2
Molecular Weight	281.06 g/mol
Synonyms	2-(2,6-Dichlorophenyl)-5-(trifluoromethyl)-1H-imidazole; 5-(Trifluoromethyl)-2-(2,6-dichlorophenyl)imidazole; 2,6-Dichloro-α,α,α-trifluoro-2'-imidazolyltoluene; 2-(2,6-Dichlorophenyl)-5-trifluoromethylimidazole; 2-(2,6-Dichlorophenyl)-5-(trifluoromethyl)imidazole; 5-Trifluoromethyl-2-(2,6-dichlorophenyl)imidazole
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 2-(2,6-Dichlorophenyl)-5-(Trifluoromethyl)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.