Description

n-(Diphenylmethylene)Glycerine tert-Butyl Ester is a specialized, high-value chemical intermediate featuring a protected glycerol backbone. This compound matters for its role as a versatile building block in sophisticated organic synthesis, enabling the controlled introduction of glycerol derivatives under demanding reaction conditions. Pharmaceutical, agrochemical, and advanced material researchers need it for developing active ingredients, chiral auxiliaries, and functional polymers where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Key synthon for the production of active pharmaceutical ingredients (APIs), particularly in nucleoside and lipid-based drug development.
• Chiral Auxiliary & Ligand Precursor: Serves as a starting material for synthesizing chiral catalysts and ligands used in asymmetric synthesis.
• Polymer Chemistry: Building block for specialty polymers and dendrimers, imparting specific solubility and functional group characteristics.
• Agrochemical Synthesis: Intermediate in the creation of advanced herbicides, fungicides, and plant growth regulators.
• Protecting Group Strategy: Utilized in multi-step organic synthesis where selective protection and deprotection of diols or polyols are required.
• Material Science Research: Used in R&D for novel surfactants, lubricant additives, and liquid crystal compounds.

Basic Information

Product Name	n-(Diphenylmethylene)Glycerine tert-Butyl Ester
CAS No.	81477-94-3
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-tert-butyl-sn-glycerol; 3-(tert-Butoxy)-1,2-O-(1-methylethylidene)-sn-glycerol; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl tert-butyl ether; Glycerol 1,2-acetonide 3-tert-butyl ether; sn-Glycerol 1,2-acetonide 3-tert-butyl ether; tert-Butyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl ether; (R)-(-)-1,2-Isopropylidene-3-O-tert-butylglycerol
EINECS	Contact for details

Quality Control

Our n-(Diphenylmethylene)Glycerine tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.