Description

tert-Butyl n-[3-(Tosyloxy)Propyl]Carbamate is a versatile and high-purity chemical intermediate, primarily used in advanced organic synthesis. Its value lies in its bifunctional structure, which incorporates both a protected amine group and a reactive tosylate leaving group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially for introducing propylamine linker segments.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like structures and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Linker Chemistry: Facilitates the creation of specialized ligands for catalysis and molecular linkers for bioconjugation.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties.
• Custom Synthesis & Scale-Up: A critical starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects from lab to commercial scale.

Basic Information

Product Name	tert-Butyl n-[3-(Tosyloxy)Propyl]Carbamate
CAS No.	80909-96-2
Molecular Formula	C15H23NO5S
Molecular Weight	329.41 g/mol
Synonyms	tert-Butyl (3-((4-methylphenyl)sulfonyloxy)propyl)carbamate; N-Boc-3-(p-toluenesulfonyloxy)propylamine; 1-[(tert-Butoxycarbonyl)amino]-3-(p-toluenesulfonyloxy)propane; Boc-NH-(CH2)3-OTs; 3-[(tert-Butoxycarbonyl)amino]propyl 4-methylbenzenesulfonate; N-(3-Hydroxypropyl)carbamic Acid tert-Butyl Ester 3-Tosylate; BOC-3-aminopropyl tosylate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[3-(Tosyloxy)Propyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP manufacturing for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.