Description

1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane-16-Carbonitrile is a specialized macrocyclic polyether compound, also known as a crown ether derivative, with a nitrile functional group. This unique structure makes it a valuable complexing agent and phase-transfer catalyst for facilitating reactions between ionic and organic species. It is primarily used by researchers and manufacturers in the pharmaceutical, fine chemical, and advanced materials sectors for synthesis, purification, and analytical applications.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Ionophore for Sensor Development: Used in the fabrication of ion-selective electrodes and chemical sensors for detecting specific cations.
• Complexing Agent in Separation Science: Employed in chromatography and extraction processes to selectively bind and separate metal ions or organic molecules.
• Building Block for Advanced Materials: Serves as a precursor or functional component in the synthesis of supramolecular structures and polymers.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules where its macrocyclic structure can influence bioavailability or targeting.
• Research & Development: A key reagent in academic and industrial R&D for studying host-guest chemistry and catalytic mechanisms.

Basic Information

Item	Details
Product Name	1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane-16-Carbonitrile
CAS No.	80900-28-3
Molecular Formula	C13H22N2O5
Molecular Weight	286.33 g/mol
Synonyms	16-Cyano-1,4,7,10,13-pentaoxa-16-azacyclooctadecane; Aza-18-crown-6-ether nitrile; 1-Aza-18-crown-6-16-carbonitrile; 16-Cyano-1,4,7,10,13-pentaoxa-16-aza-cyclooctadecane; Nitrile derivative of aza-18-crown-6; Aza crown ether nitrile; Macrocyclic polyether nitrile
EINECS	Contact for details

Quality Control

Our 1,4,7,10,13-Pentaoxa-16-Azacyclooctadecane-16-Carbonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.