Description

2-(4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid is a specialized organic acid building block featuring a unique phenyl-substituted tetrahydropyran ring system. This compound is valued for its structural complexity, which makes it a versatile intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the development of specialty polymers and advanced organic materials with specific functional properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-(4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid
CAS No.	80813-10-1
Molecular Formula	C₁₃H₁₆O₃
Molecular Weight	220.26 g/mol
Synonyms	4-Phenyltetrahydro-2H-pyran-4-acetic acid; 2-(4-Phenyltetrahydro-2H-pyran-4-yl)acetic acid; 4-Carboxymethyl-4-phenyltetrahydropyran; 4-Phenyl-4-(carboxymethyl)tetrahydropyran; 80813-10-1; 4-Phenyltetrahydropyran-4-acetic acid; (4-Phenyltetrahydro-2H-pyran-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Phenyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.