Description

3'-o-(β-Hydroxyethyl)Diosmin is a chemically modified derivative of the natural flavonoid diosmin, designed to enhance its bioavailability and pharmacological profile. This compound is valued for its potent venotonic and vascular protective properties, making it a key intermediate in advanced pharmaceutical development. It is primarily targeted at manufacturers in the pharmaceutical and nutraceutical industries seeking to develop next-generation vascular health supplements and therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical starting material for the synthesis of advanced venotonic and vasoprotective drugs.
• Dietary Supplement Formulation: Used in high-end nutraceuticals aimed at supporting circulatory health and capillary integrity.
• Cosmeceutical Active Ingredient: Incorporated into skincare products for its anti-inflammatory and capillary-strengthening benefits, targeting redness and under-eye circles.
• Research & Development: Serves as a reference standard and a key molecule for pharmacological studies in vascular biology and flavonoid metabolism.

Basic Information

Product Name	3'-o-(β-Hydroxyethyl)Diosmin
CAS No.	80604-68-8
Molecular Formula	C29H34O16
Molecular Weight	638.57 g/mol
Synonyms	3'-O-(2-Hydroxyethyl)diosmin; Diosmin 3'-O-β-hydroxyethyl ether; Hydroxyethyldiosmin; 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-[(2-hydroxyethoxy)methoxy]phenyl)-4H-1-benzopyran-4-one; Venosmine (related derivative); Modified Diosmin; Hesperidin derivative
EINECS	Contact for details

Quality Control

Our 3'-o-(β-Hydroxyethyl)Diosmin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.