Description

1-(Malonylamino)Cyclopropane-1-Carboxylic Acid is a specialized cyclopropane derivative that serves as a valuable synthetic intermediate and building block in advanced organic synthesis. Its unique structure, featuring both a malonylamino and a carboxylic acid functional group on a strained cyclopropane ring, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the cyclopropane scaffold can impart metabolic stability and conformational rigidity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for creating bioactive compounds.
• Peptidomimetics & Bio-conjugation: The carboxylic acid and amino groups facilitate its incorporation into peptide analogs or its use as a linker for bioconjugation strategies in probe and therapeutic agent development.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying biological pathways and protein functions.
• Academic & Contract Research: A critical reagent for methodological development and exploratory synthesis in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	1-(Malonylamino)Cyclopropane-1-Carboxylic Acid
CAS No.	80550-27-2
Molecular Formula	C7H9NO5
Molecular Weight	187.15 g/mol
Synonyms	1-(Malonylamino)cyclopropanecarboxylic acid; 1-Carboxy-1-(malonylamino)cyclopropane; Cyclopropanecarboxylic acid, 1-(malonylamino)-; 1-(Malonylamino)cyclopropane-1-carboxylic acid; ACC (in specific biochemical contexts, related to aminocyclopropane carboxylate); Malonyl-ACC; 1-Amino-2-carboxycyclopropane-1-malonic acid (tautomeric form); 80550-27-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1-(Malonylamino)Cyclopropane-1-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support cGMP and ISO compliant processes for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.