Description

2-[2-(Trimethylsilyl)Ethylthio]Acetic Acid Methyl Ester is a specialized organosilicon compound that serves as a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. Its unique structure, featuring both a silyl group and a thioether linkage, makes it a versatile building block for constructing complex molecules with tailored properties. This chemical is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where silicon-containing moieties or thioether linkages are required for bioactivity or metabolic stability.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel pesticides, herbicides, and fungicides, leveraging its silicon group for enhanced lipophilicity.
• Advanced Material Precursor: Employed in the production of functionalized polymers, silicone-based materials, and surface-modifying agents.
• Organic Synthesis Reagent: Acts as a versatile building block and protecting group for carboxylic acids and other functional groups in multi-step synthetic routes.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Research: A critical tool in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-[2-(Trimethylsilyl)Ethylthio]Acetic Acid Methyl Ester
CAS No.	80496-49-7
Molecular Formula	C8H18O2SSi
Molecular Weight	206.38 g/mol
Synonyms	Methyl 2-((2-(trimethylsilyl)ethyl)thio)acetate; Methyl [2-(Trimethylsilyl)ethylthio]acetate; Acetic acid, 2-[2-(trimethylsilyl)ethylthio]-, methyl ester; 2-((2-(Trimethylsilyl)ethyl)thio)acetic acid methyl ester; (2-Trimethylsilylethylthio)acetic acid methyl ester; Methyl (2-trimethylsilylethylthio)acetate; TMS-Et-S-CH2-COOMe
EINECS	Contact for details

Quality Control

Our production of 2-[2-(Trimethylsilyl)Ethylthio]Acetic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.