Description

6-Acetylthiohexanoic Acid is a versatile sulfur-containing organic acid derivative that serves as a critical building block in advanced chemical synthesis. Its bifunctional structure, featuring both a protected thiol and a carboxylic acid group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of prodrugs and active pharmaceutical ingredients (APIs), particularly those requiring thiol or disulfide linkages for targeted delivery or activity.
• Bioconjugation & Protein Modification: Used to introduce thiol-reactive handles onto biomolecules for drug-antibody conjugates (ADCs) or diagnostic probes.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing specialty polymers, coatings, and hydrogels with specific mechanical or responsive properties.
• Agrochemical Synthesis: Intermediate in the production of novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Research & Development: A valuable tool compound in organic chemistry and medicinal chemistry research for exploring new synthetic pathways.

Basic Information

Product Name	6-Acetylthiohexanoic Acid
CAS No.	80441-57-2
Molecular Formula	C8H14O3S
Molecular Weight	190.26 g/mol
Synonyms	6-(Acetylthio)hexanoic Acid; 6-Acetylsulfanylhexanoic Acid; 6-Mercaptohexanoic Acid S-Acetate; Acetylthiohexanoic Acid; S-Acetyl-6-mercaptohexanoic Acid; NSC 334365; Hexanoic acid, 6-(acetylthio)-
EINECS	Contact for details

Quality Control

Our 6-Acetylthiohexanoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.