Description

3-Chloro-5-Isoxazolepropanoic Acid is a versatile heterocyclic carboxylic acid building block, serving as a critical intermediate in advanced organic synthesis. Its unique isoxazole core functionalized with a chlorinated propanoic acid side chain makes it a valuable precursor for developing novel active compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactive isoxazole moiety.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Chelator Precursor: The carboxylic acid functionality allows for derivatization into chelating agents or ligands for metal catalysis.
• Material Science Applications: Potential use in the synthesis of specialty polymers or functional materials with specific chemical properties.

Basic Information

Product Name	3-Chloro-5-Isoxazolepropanoic Acid
CAS No.	80403-82-3
Molecular Formula	C6H6ClNO3
Molecular Weight	175.57 g/mol
Synonyms	3-Chloro-5-(2-carboxyethyl)isoxazole; 5-(2-Carboxyethyl)-3-chloroisoxazole; 3-Chloro-5-isoxazolepropionic Acid; β-(3-Chloro-5-isoxazolyl)propionic Acid; 3-Chloro-5-isoxazolylpropanoic Acid; 80403-82-3 (CAS); 3-Chloro-5-isoxazolepropanoic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Isoxazolepropanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by IR spectroscopy, and control of residual solvents and moisture content. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.