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4H-1-Benzopyran-4-One, 2-(2,6-Dihydroxyphenyl)-2,3-Dihydro-3,5,7-Trihy Droxy-, (2R,3R)- CAS NO 80366-15-0


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CAS No.:80366-15-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4H-1-Benzopyran-4-One, 2-(2,6-Dihydroxyphenyl)-2,3-Dihydro-3,5,7-Trihy Droxy-, (2R,3R)- is a high-purity, stereochemically defined flavonoid compound of significant interest in advanced research and development. This compound matters for its role as a key chiral intermediate and reference standard in the synthesis and study of bioactive natural products. It is primarily needed by R&D chemists and quality control laboratories in the pharmaceutical, nutraceutical, and fine chemical industries.

Application

  • Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel therapeutic agents and complex natural product derivatives.
  • Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC and LC-MS analyses within pharmaceutical and botanical extract laboratories.
  • Biochemical Research: Employed in studies investigating flavonoid metabolism, antioxidant mechanisms, and structure-activity relationships (SAR) due to its specific stereochemistry.
  • Nutraceutical Development: Acts as a high-purity standard for the authentication and standardization of flavonoid-rich dietary supplements and functional food ingredients.
  • Fine Chemical Synthesis: Utilized in asymmetric synthesis and catalysis research to develop new methodologies for constructing complex oxygen-containing heterocycles.

Basic Information

Product Name 4H-1-Benzopyran-4-One, 2-(2,6-Dihydroxyphenyl)-2,3-Dihydro-3,5,7-Trihy Droxy-, (2R,3R)-
CAS No. 80366-15-0
Molecular Formula C15H12O7
Molecular Weight 304.25 g/mol
Synonyms (2R,3R)-Taxifolin; (2R,3R)-Dihydroquercetin; (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone; (2R,3R)-2,3-Dihydroquercetin; (2R,3R)-Distylin; (2R,3R)-trans-Dihydroquercetin; (2R,3R)-trans-Taxifolin; (2R,3R)-trans-3,5,7,3',4'-Pentahydroxyflavanone
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Quality Control

Our (2R,3R)-Taxifolin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% (2R,3R)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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