Description

Cyclopropanecarbonitrile, 3-(Dichloroacetyl)-2,2-Dimethyl-, trans- (9Ci) is a specialized organic nitrile building block featuring a dichloroacetyl-substituted cyclopropane ring. This compound is valued for its unique sterically constrained structure, which makes it a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals. It is primarily sought by research and development chemists and process engineers in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for constructing novel molecules with targeted biological activity.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides and plant growth regulators, leveraging the reactivity of the dichloroacetyl and nitrile groups.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly those requiring a rigid, three-dimensional cyclopropane scaffold.
• Fine Chemical Synthesis: Serves as a versatile intermediate in custom synthesis and contract manufacturing for producing specialty chemicals.
• Chemical Research: Employed in academic and industrial R&D labs for studying cyclopropane chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Cyclopropanecarbonitrile, 3-(Dichloroacetyl)-2,2-Dimethyl-, trans- (9Ci)
CAS No.	80345-45-5
Molecular Formula	C8H9Cl2NO
Molecular Weight	206.07 g/mol
Synonyms	trans-3-(Dichloroacetyl)-2,2-dimethylcyclopropanecarbonitrile; 2,2-Dimethyl-3-(dichloroacetyl)cyclopropanecarbonitrile; 3-(Dichloroacetyl)-2,2-dimethylcyclopropanecarbonitrile; Cyclopropanecarbonitrile, 3-(dichloroacetyl)-2,2-dimethyl-, (1R,3R)-rel-; (1R,3R)-rel-3-(Dichloroacetyl)-2,2-dimethylcyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Quality is verified through advanced analytical techniques including HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.