Description

Defucogilvocarcin V is a specialized member of the gilvocarcin class of natural product antibiotics, characterized by its unique molecular framework. This compound is of significant interest in advanced pharmaceutical research and development due to its potent biological activity profile. It serves as a critical intermediate and reference standard for researchers in oncology, microbiology, and medicinal chemistry exploring novel therapeutic agents.

Application

• Pharmaceutical R&D Intermediate: Serves as a key building block or precursor in the synthesis of novel antibiotic and anticancer drug candidates.
• Biological Reference Standard: Used as an analytical standard in HPLC, LC-MS, and NMR for quality control and metabolic studies of gilvocarcin-related compounds.
• Mechanistic Studies: Employed in biochemical and cellular assays to investigate the mode of action of DNA-binding antibiotics.
• Academic & Institutional Research: Utilized in university and research institute laboratories for studies in natural product chemistry and pharmacology.
• Biotech Screening Libraries: Included in compound libraries for high-throughput screening against various bacterial strains and cancer cell lines.

Basic Information

Product Name	Defucogilvocarcin V
CAS No.	80155-95-9
Molecular Formula	C27H24O9
Molecular Weight	492.47 g/mol
Synonyms	Defucogilvocarcin V; 4-Demethylgilvocarcin V; Antibiotic LL-D05139 gamma; LL-D05139γ; NSC 339638; 5,6,11,12-Tetrahydro-12-hydroxy-11-methyl-6,11-epoxybenzo[b]fluoren-5-yl β-D-glucopyranosiduronic acid; (5R,6S,11R,12S)-12-Hydroxy-11-methyl-6,11-epoxy-5,6,11,12-tetrahydrobenzo[b]fluoren-5-yl β-D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our Defucogilvocarcin V is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and integrity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.