Description

4-(Aminomethyl)Chroman-4-Ol Hydrochloride is a chiral amino alcohol derivative, serving as a critical pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its unique bicyclic chroman structure, which provides a rigid scaffold for constructing molecules with potential biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the development of new active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Chiral Auxiliary/Synthon: Utilized in asymmetric synthesis to induce chirality in target molecules due to its defined stereogenic centers.
• Agrochemical Development: Intermediate in the research and production of advanced pesticides and herbicides.
• Ligand for Catalysis: Potential precursor for chiral ligands used in metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Used in the multistep synthesis of complex natural products and specialty chemicals.
• Bioconjugation & Probe Development: The aminomethyl group allows for functionalization and conjugation in biochemical applications.

Basic Information

Product Name	4-(Aminomethyl)Chroman-4-Ol Hydrochloride
CAS No.	80096-60-2
Molecular Formula	C11H15NO2·HCl
Molecular Weight	229.70 g/mol
Synonyms	4-(Aminomethyl)-4-hydroxy-3,4-dihydro-2H-1-benzopyran hydrochloride; 4-(Aminomethyl)-4-hydroxychroman hydrochloride; 4-Hydroxy-4-(aminomethyl)chroman hydrochloride; Chroman-4-ol, 4-(aminomethyl)-, hydrochloride; 4-Aminomethyl-4-hydroxychroman HCl; 4-(Aminomethyl)-4-chromanol hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Chroman-4-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.