Description

4-Bromo-n-(2-Methylbut-3-Yn-2-Yl)Benzamide is a specialized organic building block featuring a benzamide core substituted with a bromine atom and a 2-methylbut-3-yn-2-yl group. This compound is valued for its unique molecular architecture, which combines halogen functionality with an alkyne handle, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive bromine and alkyne groups for structural diversification.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) due to the bromoarene moiety.
• Ligand and Catalyst Development: Utilized as a scaffold for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Life Sciences Tool: Can be incorporated into probes or tags for biochemical and bioconjugation studies.

Basic Information

Product Name	4-Bromo-n-(2-Methylbut-3-Yn-2-Yl)Benzamide
CAS No.	80045-50-7
Molecular Formula	C₁₂H₁₂BrNO
Molecular Weight	266.14 g/mol
Synonyms	4-Bromo-N-(2-methylbut-3-yn-2-yl)benzamide; N-(2-Methyl-3-butyn-2-yl)-4-bromobenzamide; 4-Bromo-N-(1,1-dimethyl-2-propynyl)benzamide; Benzamide, 4-bromo-N-(2-methyl-3-butyn-2-yl)-; 80045-50-7; 4-Bromo-N-(2-methylbut-3-yn-2-yl)benzene-1-carboxamide
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-(2-Methylbut-3-Yn-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.