Description

(S)-1,4,7,10,13-Pentaoxacyclopentadecane-2-Methanol is a chiral crown ether derivative, a highly specialized class of macrocyclic compounds known for their selective molecular recognition properties. This compound is valued for its ability to form stable, selective complexes with specific cations and chiral molecules, making it a critical tool in advanced separation and analytical chemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical, chemical synthesis, and analytical instrumentation sectors for applications requiring high-purity chiral resolution and phase-transfer catalysis.

Application

• Chiral Phase-Transfer Catalyst: Used in asymmetric synthesis to facilitate reactions with high enantioselectivity, critical for producing single-enantiomer pharmaceutical intermediates.
• Chiral Stationary Phase (CSP) Component: Incorporated into HPLC and GC columns for the analytical and preparative separation of enantiomers in drug development and quality control.
• Ion-Selective Electrode/Sensor: Serves as an ionophore in sensor membranes for the selective detection and measurement of specific alkali or alkaline earth metal ions.
• Molecular Recognition Studies: Employed in academic and industrial research to study host-guest chemistry, supramolecular assembly, and enzyme mimicry.
• Metal Ion Extraction & Separation: Used in solvent extraction processes for the selective recovery, purification, or removal of specific metal ions from complex mixtures.
• Polymer Modification: Can be grafted onto polymer backbones to create smart materials with ion-selective or chiral recognition capabilities for specialized membranes.

Basic Information

Item	Detail
Product Name	(S)-1,4,7,10,13-Pentaoxacyclopentadecane-2-Methanol
CAS No.	80004-03-1
Molecular Formula	C14H28O7
Molecular Weight	308.37 g/mol
Synonyms	(S)-15-Crown-5-2-Methanol; (S)-(+)-2-Hydroxymethyl-15-crown-5; (S)-2-(Hydroxymethyl)-1,4,7,10,13-pentaoxacyclopentadecane; (S)-Monohydroxy-15-crown-5; L-15-Crown-5-2-Methanol; (S)-15-Crown-5 Ether Methanol Derivative; (S)-HME-15-Crown-5; (2S)-2-(Hydroxymethyl)-1,4,7,10,13-pentaoxacyclopentadecane
EINECS	Contact for details

Quality Control

Our (S)-1,4,7,10,13-Pentaoxacyclopentadecane-2-Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and process standards. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.