Description

N-(4-Chloro-2-Nitrophenyl)Acetamide is a key organic intermediate characterized by its distinct chloro and nitro substituents on the aromatic ring. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists, process development engineers, and manufacturers in fine chemical production for creating active pharmaceutical ingredients (APIs), dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with chloro- and nitro-aniline pharmacophores.
• Agrochemical Synthesis: Serves as a building block for developing herbicides, pesticides, and fungicides, leveraging its reactive nitro and chloro groups for further functionalization.
• Dye and Pigment Manufacturing: Used in the production of azo dyes and other complex colorants where the nitro group is essential for chromophore development.
• Research & Development: A valuable reagent in organic chemistry research for studying nucleophilic aromatic substitution reactions and synthesizing novel heterocyclic compounds.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing specialty chemicals with specific aromatic substitution patterns.
• Material Science: Potential intermediate in the synthesis of organic electronic materials or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	N-(4-Chloro-2-Nitrophenyl)Acetamide
CAS No.	881-51-6
Molecular Formula	C8H7ClN2O3
Molecular Weight	214.61 g/mol
Synonyms	4'-Chloro-2'-nitroacetanilide; N-Acetyl-4-chloro-2-nitroaniline; 2-Nitro-4-chloroacetanilide; Acetamide, N-(4-chloro-2-nitrophenyl)-; 4-Chloro-2-nitroacetanilide; 1-Acetamido-4-chloro-2-nitrobenzene; p-Chloro-o-nitroacetanilide
EINECS	212-921-7

Quality Control

Our N-(4-Chloro-2-Nitrophenyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for synthetic intermediates. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance in cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.