Description

17β-(Acetyloxy)-6α-Fluoroandrost-4-En-3-One is a high-purity synthetic steroid intermediate with significant pharmaceutical relevance. This compound is valued for its role as a key building block in the synthesis of more complex, potent corticosteroid and anti-inflammatory agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development and production of advanced steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent glucocorticoids and other steroidal drugs.
• Corticosteroid Research: Used in academic and industrial research to study structure-activity relationships (SAR) and develop new anti-inflammatory compounds.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid manufacturing under GMP conditions.
• Biochemical Studies: Utilized in metabolic and receptor-binding studies to understand steroid hormone action and metabolism.

Basic Information

Product Name	17β-(Acetyloxy)-6α-Fluoroandrost-4-En-3-One
CAS No.	855-55-0
Molecular Formula	C21H29FO3
Molecular Weight	348.45 g/mol
Synonyms	6α-Fluoro-17β-acetoxyandrost-4-ene-3-one; 6α-Fluoro-17β-hydroxyandrost-4-ene-3-one 17-acetate; 6α-Fluoroandrost-4-ene-3,17-dione 17-monoacetate; Fluoxymesterone Acetate (related intermediate); 6α-Fluoro-17α-methyltestosterone acetate intermediate; 6-Fluoro-17β-acetoxyandrost-4-en-3-one; 855-55-0; 6α-Fluoro-17β-acetoxy-4-androsten-3-one
EINECS	Contact for details

Quality Control

Our 17β-(Acetyloxy)-6α-Fluoroandrost-4-En-3-One is produced and tested to meet the stringent requirements of pharmaceutical intermediate applications. We employ rigorous analytical controls, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each batch to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.