Description

2-Methyl-2-Phenylbutanoic Acid is a versatile organic acid building block characterized by its unique tertiary α-carbon structure. This compound is valued for its role as a key chiral intermediate in the synthesis of complex molecules, offering significant utility in advanced chemical manufacturing. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in active ingredient development and fine chemical production.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators, leveraging its sterically hindered carboxylic acid group.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fragrance and Flavor Chemistry: Employed as a building block for creating esters and other derivatives with specific olfactory properties.
• Polymer Modification: Acts as a monomer or chain-transfer agent for modifying polymer properties such as solubility and thermal stability.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex, sterically hindered molecular architectures.

Basic Information

Product Name	2-Methyl-2-Phenylbutanoic Acid
CAS No.	828-41-1
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	2-Phenyl-2-methylbutyric acid; α-Methyl-α-phenylbutyric acid; 2-Methyl-2-phenylbutyric acid; DL-2-Methyl-2-phenylbutanoic acid; (±)-2-Methyl-2-phenylbutyric acid; NSC 406042; Butanoic acid, 2-methyl-2-phenyl-
EINECS	212-597-4

Quality Control

Our 2-Methyl-2-Phenylbutanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are properly sealed and handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.