Description

4-Bromo-5-Chloro-2-Nitrophenylamine is a halogenated nitroaniline derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the development of high-value functional materials and active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific electronic or steric properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aniline cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the bromo and chloro substituents can enhance biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and other complex colorants, contributing to color fastness and stability.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials due to its electron-withdrawing nitro group and halogen atoms.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings to form complex biaryl and heterocyclic structures.
• Chemical Research & Development: Fundamental building block in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Nitrophenylamine
CAS No.	827-33-8
Molecular Formula	C6H4BrClN2O2
Molecular Weight	251.47 g/mol
Synonyms	2-Amino-4-bromo-5-chloronitrobenzene; 4-Bromo-5-chloro-2-nitrobenzenamine; 1-Amino-4-bromo-5-chloro-2-nitrobenzene; 2-Nitro-4-bromo-5-chloroaniline; Benzenamine, 4-bromo-5-chloro-2-nitro-; 4-Bromo-5-chloro-2-nitroaniline; 827-33-8; 4-Br-5-Cl-2-NO2-C6H3NH2
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Nitrophenylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with global regulatory frameworks, and custom purity grades, including research and pharmaceutical intermediates, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.