Description

1-Bromo-2-Butanone is a versatile halogenated ketone building block essential for advanced organic synthesis. This compound matters for its role as a key electrophile and alkylating agent, enabling the introduction of functionalized butanone moieties into complex molecular architectures. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Production of herbicides, fungicides, and pesticide intermediates.
• Chemical Research & Development: A versatile reagent for alkylation and functional group transformation reactions in lab-scale and pilot-scale projects.
• Material Science: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Flavor & Fragrance Industry: Serves as a precursor for synthesizing specific aroma chemicals.
• Cross-coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling methodologies.

Basic Information

Product Name	1-Bromo-2-Butanone
CAS No.	816-40-0
Molecular Formula	C4H7BrO
Molecular Weight	151.00 g/mol
Synonyms	2-Oxo-1-bromobutane; Bromomethyl Ethyl Ketone; α-Bromobutan-2-one; 1-Bromo-2-oxobutane; Ethyl Bromomethyl Ketone; Bromoethyl Methyl Ketone; 2-Butanone, 1-bromo-; NSC 60548
EINECS	212-432-2

Quality Control

Our 1-Bromo-2-Butanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and highly volatile nature, containers must be kept tightly sealed and away from heat and ignition sources.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.40 - 1.45
Refractive Index (n20D)	1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.