Description

Sennoside A CAS NO 81-27-6 is a purified, high-purity anthraquinone glycoside derived from senna leaves. This compound serves as a critical active pharmaceutical ingredient (API) and a key reference standard for quality control in pharmaceutical and nutraceutical manufacturing. It is primarily required by manufacturers in the pharmaceutical, herbal medicine, and dietary supplement industries for its well-characterized biological activity.

Application

• Active Pharmaceutical Ingredient (API) in prescription and over-the-counter laxative formulations.
• Pharmaceutical Reference Standard for the identification and assay of senna-based products in QC laboratories.
• Key Intermediate in the research and development of gastrointestinal therapeutics.
• Herbal Extract Standardization to ensure potency and consistency in botanical supplements.
• Biochemical Research for studying anthraquinone metabolism and pharmacology.
• Quality Control Reagent in the analysis of raw botanical materials and finished products.

Basic Information

Product Name	Sennoside A
CAS No.	81-27-6
Molecular Formula	C42H38O20
Molecular Weight	862.75 g/mol
Synonyms	Sennoside A; Sennoside; 6,6'-Dihydroxymethyl-8,8'-dianthrone-3,3'-dicarboxylic acid diglucoside; Rhein-8-glucoside dianthrone; (Rhein dianthrone diglucoside); Cassioside; Senna glycoside A
EINECS	201-340-0

Quality Control

Our Sennoside A is produced under strict quality management systems to ensure it meets the stringent requirements of pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific pharmacopoeial standards such as USP, EP, or JP upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.