Description

Tiglic Acid CAS NO 80-59-1 is a naturally occurring, unsaturated carboxylic acid characterized by its distinct chemical structure. This compound serves as a versatile and valuable chemical intermediate and building block in advanced organic synthesis. It is essential for manufacturers in the pharmaceutical, agrochemical, and fragrance industries seeking to develop complex molecules with specific stereochemistry and functional properties.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to biological activity.
• Flavor and Fragrance Ingredient: Employed as a precursor for creating specific ester compounds that impart unique sensory notes in fine perfumery and flavorings.
• Organic Synthesis Reagent: Utilized in Diels-Alder reactions and other cycloadditions to construct complex organic frameworks in research and development.
• Polymer Modification: Acts as a monomer or co-monomer for introducing functional groups into specialty polymers and resins.
• Chemical Research: Serves as a standard and starting material in academic and industrial laboratories for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Tiglic Acid
CAS No.	80-59-1
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(E)-2-Methyl-2-butenoic Acid; trans-2-Methyl-2-butenoic Acid; 2-Methylcrotonic Acid; Tiglinic Acid; Angelic Acid Isomer; trans-2,3-Dimethylacrylic Acid; (E)-2,3-Dimethylacrylic Acid; Crotonic acid, 2-methyl-
EINECS	201-295-0

Quality Control

Our Tiglic Acid is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep the container tightly sealed when not in use to maintain quality.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	63 - 65 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.