Description

4-(4-Cyano-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl piperidine core and cyanoaryl substituent. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Protease Inhibitor Research: Used in the construction of molecules targeting proteolytic enzymes, such as cathepsins or viral proteases.
• Kinase Inhibitor Scaffold: Serves as a core structure for developing potential kinase inhibitors in oncology and inflammatory disease research.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying enzyme function and signal transduction pathways.
• Custom Synthesis Building Block: Provides a versatile, functionalized piperidine moiety for contract research organizations (CROs) and fine chemical suppliers.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of candidate drugs.

Basic Information

Item	Information
Product Name	4-(4-Cyano-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	797750-44-8
Molecular Formula	C17H22N2O4S
Molecular Weight	350.44 g/mol
Synonyms	4-(4-Cyanobenzenesulfonyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(4-cyanophenyl)sulfonyl]piperidine-1-carboxylate; 1-Boc-4-(4-cyanobenzenesulfonyl)piperidine; 4-(4-Cyanophenylsulfonyl)piperidine-1-carboxylic acid tert-butyl ester; 4-(4-Cyano-benzenesulfonyl)-piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-cyanobenzenesulfonyl)piperidine; 797750-44-8
EINECS	Contact for details

Quality Control

Our 4-(4-Cyano-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.